In a city of buttoned-down conformity, Manon Cleary represented an iconoclastic vision of Washington life. She was an acclaimed artist, known for her stark self-portraits painted with breathtaking realism, and for decades was one of the most alluring figures in Washington’s art world.

She had a remarkable ability to draw and paint with photographic fidelity, but she was also known as a charismatic teacher at the University of the District of Columbia and as a free spirit whose exuberant life may have been her most enduring work of art.

Ms. Cleary died Nov. 26 at her home in the District at age 69. She had chronic obstructive pulmonary disease, said her husband, F. Steven Kijek.

Since the 1970s, Ms. Cleary — whose first name is pronounced “muh-NAHN” — had been at the center of a group of artists in Adams Morgan. She exhibited her meticulous artwork throughout the city and around the world, but she also became known for her striking presence, her colorful love life and the rats she kept as pets.

As an artist, Ms. Cleary borrowed classical techniques from her deep study of Renaissance masters to create paintings and drawings memorable for their frank realism and sometimes disturbing themes.

In a city of buttoned-down conformity, Manon Cleary represented an iconoclastic vision of Washington life. She was an acclaimed artist, known for her stark self-portraits. (Photo by Paul Feinberg/PHOTO BY PAUL FEINBERG)

In addition to her many nude self-portraits, Ms. Cleary made erotically charged paintings of flowers. She took inspiration from a painful personal history in a series of works depicting the terror of rape and, in later years, of not being able to breathe without mechanical assistance.

Critics considered her a leading figurative artist of the photo-realist school, in which painters render their subjects with camera-like precision. In fact, Ms. Cleary occasionally won awards for photography when adjudicators didn’t realize her works were free-hand creations.

She was “widely acknowledged to be among the best, if not the best, of the city’s figurative painters,” Washington Post critic Michael O’Sullivan wrote in 2006. “There is a tension between the cool, clinical detachment of photography and painting’s warm idealization of form.”

Ms. Cleary exhibited her art in galleries and museums from Moscow to Paris to Hickory, N.C., but Washington was her home for the past 42 years.

In 1974, she settled in the decrepit Beverly Court apartments on Columbia Road NW, where a coterie of artists soon grew up around her. She painted her walls purple, and her fourth-floor apartment — even with the pet rats — became something of a bohemian salon.

“She was a star,” painter Judy Jashinsky told the Washington City Paper in 2004. “She was stunning, beautiful; long, brownish–black hair; real thin; wore . . . little sundresses and sandals. She was just very cool, and there was always a crowd around her.”

Ms. Cleary had a long list of male admirers, including several whose confrontational attempts at “performance art” led to their arrests. She had a brief marriage in 1981 to a Danish artist known as Tommy — “just Tommy,” Ms. Cleary said — whom she divorced in less than a year.

As a kind of graphic homage to her various lovers, Ms. Cleary made a series of intimately revealing portraits that were featured years later on the HBO program “Real Sex.”

She met her second husband after a gallery opening in Baltimore. By way of introduction, Kijek, a dancer, stripped naked at a crowded party, walked up to Ms. Cleary and said, “Wouldn’t you like me to pose for you?”

They were married in 2001. Her husband and a twin sister are Ms. Cleary’s only survivors.

In spite of her unconventional life, Ms. Cleary was more than a mere provocateur. After a day of teaching at UDC, she would return to her studio, with its windows painted over to block out sunlight, and work late into the night, with a bottle of Dr Pepper at her side.

She took nude photographs of herself from every angle, then painstakingly created lifelike images that seemed alive with the warmth of human flesh.

After studying in Rome in her youth, she developed what she called “an obsession” with Caravaggio, an iconoclastic painter who lived from 1573 to 1610. She often copied paintings at the National Gallery of Art and, in her own work, blended Renaissance styles with a distinctly modern sensibility.

Ms. Cleary’s “Rape” series from the late 1990s grew out of a sexual assault she suffered in 1996 while lecturing in Kazakhstan. Several of the black-and-white works show Ms. Cleary screaming; others are spattered with red paint, and one contains nails driven into her face.

“They are gut-wrenching, primal works, imbued with a distillation of fear, pain, guilt, sorrow and hatred,” critic Ferdinand Protzman wrote in The Post when the paintings were exhibited at George Mason University in 1998. “They are horrifying and unforgettable.”

Manon Catherine Cleary was born Nov. 14, 1942, in St. Louis. Her father was a doctor, and her identical twin sister, Shirley Cleary-Cooper, is an artist in Helena, Mont.

She was a 1964 graduate of Washington University in her home town and, for the rest of her life, was proud of having been a member of the Pi Phi sorority. After teaching at a junior high school near St. Louis, she studied in Italy and Spain and received a master of fine arts degree from Temple University in Philadelphia in 1968.

Some of Ms. Cleary’s works are in the collections of museums, including the Corcoran Gallery of Art, National Museum of Women in the Arts, the Brooklyn Museum and Chicago Art Institute.

After being given a rat as a pet in the 1970s, Ms. Cleary made rats a recurring subject of her art, often in large-scale paintings, with each hair shown in luminous detail. Once, when an art gallery replaced one of Ms. Cleary’s self-portraits with a painting of a rat, the label “Self-Portrait” was left on the wall.

“All of my work has been about self — even the rats,” she told Washingtonian magazine in 2005. “I do have a rat nose and rat hands.”

Ms. Cleary was a heavy smoker and worked for many years in an unventilated studio with chemical solvents and fixatives. After being diagnosed with chronic obstructive pulmonary disease in 1999, she had to give up teaching after 30 years at UDC. She was dependent on breathing tubes and oxygen tanks for the remainder of her life.

With little energy for painting and drawing, Ms. Cleary found new forms of expression. By pressing her face and breathing tube on the glass of a copy machine, she created a new series of distorted self-portraits that she called “Breathless.”

Over the years, as a teacher, mentor and member of the advisory committee of Washington’s Hillyer Art Space, Ms. Cleary advanced the careers of dozens of younger artists.

“If she saw talent, she would really support it and promote it,” Washington art collector and gallery owner Fernando Batista said in an interview. “She tied together so many groups, older and younger. There are very few people like that.”

Even with the pet rats, Ms. Cleary’s candle-lit apartment became known as a gathering place for an ever-changing group of Washington artists.

“I keep the light levels low all the time — curtains drawn except in the dining room, where the plants need sun, and windows painted over in my studio,” she told The Post in 1998. “And I entertain at night, when dust doesn’t show.”