A shooting on Route 50 in Prince George’s County that sent three men to hospitals shut down the busy highway for five hours during Thursday’s evening commute, authorities said.

The shooting occurred in the eastbound lanes of Route 50, near Columbia Park Road, just east of the Baltimore-Washington Parkway, according to the Prince George’s County Police Department’s Twitter account.

The driver of a four-door sedan and two passengers suffered wounds, but police believe the injuries were not life threatening, said Officer Tyler Hunter, a spokesman. Police do not believe the shooting was random or a road-rage incident, he said.

Eastbound Route 50 was closed from about 3 p.m., when the incident occurred, until about 7:45 p.m., Hunter said. Authorities towed away the victims’ vehicle to process it for evidence, he said.

Police believe the shots were fired from a second vehicle, near the overpass at Columbia Park Road, but police did not release a description of the car. Investigators were still seeking a motive for what might have prompted the shootings, Hunter said.

Mapping homicides in the District and the surrounding suburbs since 2000.

Staff Writer Clarence Williams contributed to this report.

This report has been udpated.