The novel coronavirus has caused about 285,000 more deaths in the United States between Feb. 1 and Sept. 16 than in an average year, according to a report Tuesday, released by the Centers for Disease Control and Prevention.

The health agency said people ages 25 to 44 were particularly hit hard, with an “excess death” rate shooting up 26.5 percent over that in past years. Racial and ethnic minority groups, including Black Americans and Latinos, were found to be among the hardest hit.

The report comes as the United States struggles with yet another spike in virus infections. Nearly every state is reporting more cases now than at the end of September, and most states have seen their seven-day average of new infections surge by more than 40 percent, according to data tracked and analyzed by The Washington Post. At least 10 states set records Tuesday for virus hospitalizations.

Here are some other significant developments:

  • Prospects for an economic relief package in the next two weeks dimmed markedly on Tuesday after Senate Majority Leader Mitch McConnell (R-Ky.) revealed that he has warned the White House not to strike an agreement with House Speaker Nancy Pelosi (D-Calif.) before the Nov. 3 election.
  • The latest weekly report from the White House coronavirus force says 31 U.S. states are in the “red zone,” a concerning classification that comes when a state eclipses 100 reported cases per 100,000 people in the week previous.
  • A local health department in Michigan placed students at the state’s second-largest university under a two-week stay-at-home order to slow the spread of the virus after infections in the county hit record highs.
  • British scientists will launch the world’s first human challenge trials for the coronavirus, in which healthy volunteers will be deliberately infected with the virus, in the hope of speeding to a vaccine.
  • The global tally of officially confirmed coronavirus cases surpassed 40 million on Monday amid new surges in the United States and Europe. Since February, more than 8.2 million infections and 220,000 fatalities have been reported in the United States.