After weeks of surging infections and rising levels of virus hospitalizations, the United States recorded more than 3,000 covid-19 deaths in a single day, a pandemic record, according to a Washington Post analysis.

The harrowing milestone comes as two vaccine candidates appear to be on the verge of clearing the country’s final regulatory hurdles. Yet the new death record, as well as a new high of more than 106,000 covid-19 patients in hospitals, are grim reminders of the pandemic’s devastating toll.

Here are some significant developments:

  • Canada granted interim authorization to a vaccine made by pharmaceutical giant Pfizer and its German partner, BioNTech.
  • British regulators ordered hospitals not to give the Pfizer-BioNTech vaccine to people with a history of “significant” allergic reactions after two health-care workers reacted adversely to the first dose.
  • A U.S. official said 2.9 million doses of the Pfizer-BioNTech vaccine would be going in the initial shipments following approval.
  • The State Department hosted roughly 200 guests Tuesday night at the presidential guesthouse despite concerns of public health experts.
  • At least 288,000 people have died of the coronavirus in the United States, and more than 15.3 million infections have been reported nationwide.

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