Keaton was one of several first-time winners at Sunday’s ceremony. His only other nomination came in 2003, for his performance in the HBO movie “Live from Baghdad.”
Here are the other first-time winners:
Actor, drama: Eddie Redmayne, “The Theory of Everything”
This was the first nomination for Redmayne, who portrayed the physicist Stephen Hawking.
Supporting actor, film: J.K. Simmons, “Whiplash”
The veteran character actor was a first-time nominee and took home the first award of the night.
Supporting actress, film: Patricia Arquette, “Boyhood”
Arquette had three previous nominations for her role in the TV drama “Medium.” This was her first nomination as a film actress.
Director, film: Richard Linklater, “Boyhood”
Linklater earned his first two Globe nominations this year, both for “Boyhood”; he was also nominated for best screenplay.
Actor, drama series: Kevin Spacey, “House of Cards”
The two-time Oscar winner finally won a Golden Globe, on his eighth try. “I can’t [bleeping] believe I won one,” he said.
Actress, drama series: Ruth Wilson, “The Affair”
Wilson was nominated previously in 2008 for her role as Jane Eyre in a TV miniseries.
Actor, musical or comedy series: Jeffrey Tambor, “Transparent”
This was Tambor’s first nomination.
Actress, musical or comedy series: Gina Rodriguez, “Jane the Virgin”
The 30-year old newcomer, a first-time nominee from a rookie show, beat out such established actresses as Edie Falco (“Nurse Jackie”) and Julia Louis-Dreyfus (“Veep”).
Actor, miniseries or movie: Billy Bob Thornton, “Fargo”
Thornton, who has a screenwriting Oscar, has been nominated four previous times, all for movies: “Bad Santa,” “The Man Who Wasn’t There,” “Bandits” and “A Simple Plan.”
Actress, miniseries or movie: Maggie Gyllenhaal, “The Honourable Woman”
This was Gyllenhaal’s third nomination.
Supporting actor, series, miniseries or movie: Matt Bomer, “The Normal Heart”
This was Bomer’s first nomination.
Supporting actress, series, miniseries or movie: Joanne Froggatt, “Downtown Abbey”
Froggatt’s win, the second award of the night, set the tone for the show — the first-time nominee was an upset winner over Uzo Aduba (“Orange is the New Black”).
More Golden Globes:
PHOTOS: Golden Globes red carpet 2015