The WGN America drama ‘Underground’ will be the first public program in the new museum’s theater.

A screening of the acclaimed TV drama, “Underground” will officially open the Oprah Winfrey Theater of the National Museum of African American History and Culture on Sept. 26, officials said Thursday.

The original series airs on WGN America. The screening will be followed by a panel discussion with co-creator and writer Misha Green and cast members Alano Miller (Cato), Amirah Vann (Ernestine) Jessica de Gouw (Elizabeth Hawkes) and Aisha Hinds (Harriet Tubman). The museum’s associate director Red Ellis will moderate. The screening begins at 7 p.m.

The series depicts the lives of enslaved people who risk death to reach freedom on the Underground Railroad.  In its premiere season, it was among the top cable dramas, and it has been screened at the White House, the National Underground Railroad Freedom Center and the National Civil Rights Museum. The second season is scheduled to air in early 2017.

The museum features artifacts representing Tubman, probably the most famous underground railroad operator. Tubman will have a central role in the upcoming season.

The museum plans to host musical performances, screenings and discussions in the 350-seat venue. Author Heather Ann Thompson will discuss her upcoming book, Blood in the Water: The Attica Prison Uprising of 1971 and its Legacy, and Ohio State University Professor Hassan Jeffries will interview acclaimed photographer, Stephen Shames, and Black Panther founder, Bobby Seales  about their upcoming book, Power to the People: The World of the Black Panthers.

The newest Smithsonian museum opens Sept. 24. The entrance to its theater is at 1400 Constitution Ave. NW