Television and film actress Mary Tyler Moore died Wednesday at the age of 80, and as news of her passing spread, famous friends, entertainers and media personalities took to social media to share their condolences.

Moore’s extraordinary comedic timing and role as a career woman in “The Mary Tyler Moore Show” earned her legions of fans and, as a number of contemporary broadcasters shared Wednesday, served as an inspiration to women in the journalism field.

Ed Asner, who played opposite Moore on the groundbreaking 1970s sitcom, wrote on Twitter, “my heart goes out to you and your family. Know that I love you and believe in your strength.”

Hours later, he added, “A great lady I loved and owe so much to has left us. I will miss her. I will never be able to repay her for the blessings that she gave me.”

In the 1960s, Moore played a housewife on “The Dick Van Dyke Show,” and she would eventually go on to play more dramatic roles after her run on her own sitcom. She won a Tony and an Emmy for such roles, and received an Oscar nomination in 1980.

Moore played a spunky Minneapolis local news producer on her eponymous show, a beloved character embraced by the city in real life.

Moore’s costar Cloris Leachman, who played the Phyllis Lyndstrom, said in a statement to Vanity Fair, “the picture that we all have of her, that’s how she was—sweet, kind, so tender, so delicate. She was America’s sweetheart.

On social media, several notable figures shared what Moore meant to them, and their grief at her passing.