RESIST!, THE comics anthology launched in response to President Trump’s election, will be more than a one-shot wonder.

The political zine, co-founded by New Yorker art director Françoise Mouly to spotlight female creators and issues they view as important, made its debut at the Women’s March in Washington.

Today, Resist! is announcing that a second issue will be released through its editors’ growing network of fans and followers, boosted by Maryland-based Diamond Comics Distributors. The publication date will be Independence Day as a “celebration of the First Amendment.”

“While everywhere else there may be protest fatigue, from our standpoint it seems to be an exciting moment of rebirth for comics as political activity,” Mouly tells The Post’s Comic Riffs. “It feels like a return to the Charlie Hebdo of my youth in May 1968,” during the Paris student riots.

Mouly underscores the publication’s embrace of star cartoonists and young unknowns alike. “What’s unique to Resist! is the way it mixes the voices of librarians and young girls and accountants together with that of Roz Chast, Cathy Malkasian, Miriam Katin, Daniel Clowes and Art Spiegelman,” she says.

Resist! did not take sustained interest in its mission for granted.

“We held our breath when we announced the open call for the second issue, wondering if the energy that existed after the inauguration would still be there,” says co-founder Nadja Spiegelman, who is the daughter of Mouly and her husband, Art Spiegelman.

The result? “We got even more submissions for this second issue than for the first,” says Spiegelman about the hundreds of cartoons sent. “It feels like an invigorating new moment for the feminism of my generation — one where women can be, for the first time, both angry and funny.”

The free publication is backed by volunteers, as well as comic-book shops that pre-order Resist! through Dismond. The issue’s slogan is “Women’s Voices Will be Heard.”

“It will be good for comics in general to welcome young women as creators and readers,” Mouly says“That’s where the energy is right now.”