Andrew Luck looked on in dismay Sunday night. (A.J. Mast / AP)

Indianapolis Colts wide receiver Reggie Wayne will miss the rest of the season after tearing his anterior cruciate ligament in the team’s victory over the Denver Broncos on Sunday night.

“We hate to lose anybody, but this one stings,” Colts Coach Chuck Pagano said. “You just don’t replace guys like 87. But he’ll be back, I know how he’s wired. I know how his DNA is.

“After the conversation I just had with him, wait and see. We’ll all put on the clothes for Reggie and we’ll help him get it back.”

Wayne’s quarterback, Andrew Luck, blamed himself for a poor throw that forced Wayne to come back for a pass midway through the fourth quarter. “It was my fault,” Luck said Sunday night. “Terrible throw.”

Later, he continued the self-flagellation, telling Peter King of “It stinks to the nth degree. I put a lot of blame on myself for missing that throw.”

Wayne, 34, had played in 189 straight games and had caught five passes for 50 years Sunday night. The 5-2 Colts have a bye this week and may well choose to make a trade before the Oct. 29 deadline.