Jack Hoffman was the star of Nebraska’s spring game in 2013. (Ryan Soderlin / AP)

There’s a sad setback in the story of Jack Hoffman, the 8-year-old cancer patient and 2013 ESPY winner who scored a 69-yard touchdown in a Nebraska game last year. The inspirational kid’s cancer is no longer in remission.

“Today, we were humbly reminded that when your child has an inoperable brain tumor, that anything can happen at any point in time,” Jack’s dad Andy Hoffman wrote on the Caring Bridge Web site on Wednesday. “Despite Jack’s tumor being declared in remission last October, today we learned that is no longer the case.”

The young Hoffman will now face a second round of chemotherapy, as well as a possible clinical trial treatment, Jack’s dad writes.

As soon as the news broke, Huskers fans and others took to the Web to post messages of support. One of the most moving comes from HuskerCorner.com’s Brandon Cavanaugh, who writes:

Dear Jack,

Every day when I sit down and go to work, I have several helmets, both mini and regular-sized above my computer. I have autographs from people I admire and my favorite hat. I also have the rookie card Upper Deck made for you.

That card is a constant reminder of your struggles and your fight. I know you’ve been told it a lot, but you inspire me. You inspire millions. …

As a journalist, I have to be objective in what I see, be willing to call good things good and bad things bad. I have to be professional and not show bias. However, I must admit that I am slightly flawed in that respect.

I openly root for a team that has repeatedly gone undefeated and will continue to make the opposition look the fool. I do so unapologetically.

It has the best mascot, the best jersey, every aspect of it is divine.

I root for Team Jack and it will never, ever lose.

So do we.

(H/t: ESPN)