We all know that a No. 16 seed has never beaten a No. 1 seed in the NCAA tournament’s first round. But what about the other seed pairings? Let’s go through them using The Post’s NCAA tournament database. All results go back to 1985, when the tournament expanded to 64 teams.

No. 1 vs. No. 16

Of note: The closest game was Georgetown’s one-point win over Princeton and Oklahoma’s one-point win over East Tennessee State, both in 1989. Next closest: Purdue 73, Western Carolina 71 in 1996.

No. 2 vs. No. 15

Of note: Three of those No. 15 wins came in either 2012 (Norfolk State over Missouri, Lehigh over Duke) or 2013 (Florida Gulf Coast over Georgetown).

No. 3 vs. No. 14

Of note: Two No. 14 seeds won in the same tournament only twice, in 1986 (Arkansas-Little Rock over Notre Dame, Cleveland State over Indiana) and 1995 (Weber State over Michigan State, Old Dominion over Villanova).

No. 4 vs. No. 13

Of note: A 13-4 upset happened every NCAA tournament from 2008 to 2013.

No. 5 vs. No. 12

Of note: Read all about 12-5 upsets right here. Hint: They’ve happened a lot lately.

No. 6 vs. No. 11

Of note: Since 2007, No. 6 seeds are just 18-14 against No. 11 seeds in the first round.

No. 7 vs. No. 10

Of note: In 2010, three No. 10 seeds won their first-round matchups. Since then, No. 7 seeds have gone 11-5 against No. 10s.

No. 8 vs. No. 9

Of note: Since 2011, No. 8 seeds are 11-5 vs. No. 9 seeds in the first round.