American motorcycle racer Nicky Hayden died Monday, less than a week after he was hit by a car while bicycling in Italy.

Maurizio Bufalini Hospital in Cesena confirmed the 35-year-old died as a result of the injuries — severe brain damage and trauma to the chest, pelvis and abdomen — suffered in last Wednesday’s crash.

Hayden is survived by his fiancee, Jackie, his parents and his four siblings.

The details pertaining to the Wednesday collision remain unknown, except that he was hit by a car while cycling near the Italian coastal city of Rimini. The former MotoGP champion collided with the car’s windshield.

According to a statement from Hayden’s team, Red Bull Honda World Superbike, Hayden was treated on site by emergency medical staff before transferred to a nearby hospital where he was stabilized. From there, he was transferred to the larger Bufalini facility about a 40-minute drive away.

Born in Owensboro, Ky., Hayden began his MotoGP career in 2003, where within three years he rose to the top of the field to win the 2006 MotoCP championship. Riders in MotoGP use custom motorcycles. Hayden moved down in 2016 to the Superbike level, in which riders compete on commercially available motorcycles. Hayden remained on the Superbike circuit in 2017, having competed at a race in Imola, Italy, on May 13.

Hayden’s collision with a car in Europe is the latest in a string of high-profile incidents that have cyclists worried about safety on the roads.

Last month, Italian pro cyclist Michele Scarponi was killed while training in Italy when a van driver reportedly failed to spot the 37-year-old winner of the 2011 Giro d’Italia at an intersection in near his home in Filottrano, Italy.

Days later, French pro cyclist Yoann Ofredo was assaulted by a driver and her passenger while training outside of Paris. The cyclist was not seriously injured in the incident, but sustained cuts and bruises.

Two weeks ago, three-time Tour de France winner Chris Froome claimed he was “rammed on purpose” by a vehicle while riding in Beausoleil, France, not far from his residence in Monaco. While his bicycle was totaled, Froome came away from the incident unharmed.

Missy Khamvongsa contributed to this report.