(Photo by John McDonnell/The Washington Post)

With the Astros starting left-hander Brett Oberholtzer, right-handed hitter Steven Souza Jr. will get his first career start, playing right field. Kevin Frandsen will man left for the second straight night, and Tyler Moore is in for Adam LaRoche. Every left-handed regular is off except Denard Span, who has a .502 OPS since he came off the disabled list.

Nationals

1. Denard Span, CF

2. Anthony Rendon, 3B

3. Jayson Werth, DH

4. Ian Desmond, SS

5. Tyler Moore, 1B

6. Kevin Frandsen, LF

7. Danny Espinosa, 2B

8. Sandy Leon, C

9. Steven Souza Jr., RF

– Jordan Zimmermann, SP

Astros

1. Jose Altuve, 2B

2. Dexter Fowler, CF

3. Jason Castro, C

4. George Springer, RF

5. Jesus Guzman, 1B

6. Alex Presley, LF

7. Chris Carter, DH

8. Matt Dominguez, 3B

9. Jonathan Villar, SS

– Brett Oberholtzer, SP