The National Hurricane Center's projected path for Tropical Storm Issac.

On Wednesday, Tampa's mayor Bob Buckhorn said he's "prepared to call it off" (it being the Republican National Convention) should Tropical Storm Isaac hit. But Republican National Committee Communications Director Sean Spicer is more bullish.

"There is no such thing as canceling," he told CNN Thursday. "We do have contingency plans to deal with weather related and other circumstances that may occur to ensure that the business can go on at the RNC and Mitt Romney and Paul Ryan will become our nominees."