President Obama is expected to name deputy national security adviser Denis McDonough, one of his closest confidants who served in his senate and campaign offices, as his new chief of staff, associates said.

Administration officials cautioned that Obama has not made a final decision. But associates of McDonough’s said the announcement could come in the next several days that he will replace Jacob J. Lew, who was recently nominated to head the Treasury Department. Lew recently joked at a staff meeting that the 43-year-old McDonough would be inheriting all of his work-related items, one person said.

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