"Do you support the national Democratic Party platform?" asks a local blogger, Jim Pence.
"I do, Jim," Grimes says. The clip is again repeated later in the ad, after a narrator suggests Grimes is on-board with the administration's alleged "war on coal."
(The clip was discussed by McConnell aides during a secretly recorded meeting in which they discussed opposition research on Grimes and then-potential candidate Ashley Judd.)
The DSCC's online ads, meanwhile, hit McConnell as the "guardian of gridlock," pointing to the Senate GOP's frequent filibuster threats.
The buy comes as Grimes is just getting her campaign off the ground and as Republicans have been quick to try to define her candidacy.
McConnell has a huge early cash advantage on Grimes, banking $9.6 million at the end of June.
National Republicans also launched their own online campaign within hours of Grimes's announcement.
Updated at 9:51 a.m.