Kerry, who continues to push the case for intervention during his European trip, was quickly criticized for the remark by Republicans, including supporters of military intervention like House Intelligence Committee Chairman Mike Rogers (R-Mich.), who said he was effectively previewing what the response would be.
"That’s ... certainly a confusing message to me that he would offer that as somebody who believes this is in our national security interest," Rogers said on MSNBC's "Morning Joe."
Sen. John McCain (R-Ariz.), another supporter of military action, later labeled Kerry's comment "unbelievably unhelpful."
The administration has repeatedly emphasized that the United States will not be going to war in Syria and that any efforts would be limited to retaliation for the government's alleged use of chemical weapons on its own people.
But many, including members of Congress, worry that the mission would gradually expand over time.
Here's a sampling of the negative reaction on Twitter:
Updated at 11:47 a.m. with McCain's tweet.