Paul has started spats with at least this many people (Photo by Scott Olson/Getty Images)

This post has been updated. 

It's only fitting that the senator representing the home state of the McCoys - across the river from the Hatfields - likes to pick fights.

On Wednesday, Sen. Rand Paul (R) took aim at former Florida governor Jeb Bush over his Iraq war message issues. And he found time to hit another 2016 White House contender, fellow Sen. Marco Rubio (R-Fla.) over foreign policy too.

Paul likes to brawl. Granted, the other candidates have also been making their own slams this week after Jeb Bush fumbled answers about the Iraq war and it was revealed that George Stephanopoulos donated tens of thousands of dollars to the Clinton Foundation. But Paul has been hitting hard since before he even announced his candidacy, particularly against Hillary Clinton. He also likes to troll people on Twitter. Here's this week's update:

Jeb Bush 

Paul slammed Bush in numerous interviews Wednesday about his statements on the Iraq war, saying Bush's message had been "incredibly fumbled." Bush, who has not yet formally declared his candidacy, has a "real problem" if he couldn't directly answer the question of whether he would have launched an invasion of Iraq himself if he knew then what he knows now.

"To say that nothing would happen differently means we’re going to get George Bush 3," Paul said in an interview with The Associated Press. “I think what his foreign policy will be — and whether or not it’s the same as his brother’s — is very important to bring up. I think they are good questions.”

Marco Rubio

Paul also had choice words for Rubio's foreign policy Wednesday, after the Florida Republican made his first policy speech. Rubio called for foreign aid, saying he supports the "spread of economic and political freedom" and effective foreign assistance programs. It's a subject that has been tricky for Paul, who once called for an end to all foreign aid and has since calibrated his position after the specter of cutting aid to Israel became a problem. Paul now calls for substantial cuts to foreign aid, specifically to "haters of America" including Pakistan and China.

“I say he’s on the wrong side of history,” Paul said about Rubio in Politico.

George Stephanopoulos

Stephanopoulos, ABC News's chief political anchor, donated $50,000 to the Clinton Foundation in recent years. Stephanopoulos used to work in the Clinton White House. Paul told The New York Times that the donations and ties with the Clintons should bar him from moderating any presidential debates.

It’s impossible to divorce yourself from that, even if you try,” Paul said. “I just think it’s really, really hard because he’s been there, so close to them, that there would be a conflict of interest if he tried to be a moderator of any sort.”

[Read: ABC News’s Stephanopoulos donated $50,000 to Clinton Foundation]

The week's not over yet -- stay tuned.