The retired neurosurgeon's comments follow the mass shooting at Umpqua Community College last week that left nine people dead and at least 10 wounded. The gunman, who had a history of mental illness, killed himself after police officers arrived on the scene and exchanged gunfire.
The gunman reportedly singled out Christians during his shooting rampage.
Carson on Monday night took to Facebook to denounce calls for increased gun regulation in the wake of another mass shooting, saying that the problem is not caused by Second Amendment protections and accusing gun-control advocates of politicizing the tragedy.
"As a Doctor, I spent many a night pulling bullets out of bodies," he wrote. "There is no doubt that this senseless violence is breathtaking – but I never saw a body with bullet holes that was more devastating than taking the right to arm ourselves away. Serious people seek serious solutions. ...
"The Left would prefer to use these tragedies to advance a political agenda. To me, that is also devastatingly sad," he added. "The Left would have you believe that a man that asked Christians to stand up (and then executed them one by one) would obey 'new gun laws.' That kind of logic explains many of the problems we find ourselves in today."
The Carson campaign did not immediately return a request for comment.