The Democratic nominee also plans to highlight an “Autism Works” initiative that aims to extend public-private partnerships to connect people with autism to employment opportunities.
The speech is the latest in a series that Clinton is delivering in the closing months of the race designed to offer a positive agenda amid a campaign with Republican Donald Trump in which both candidates have spent considerable energy trying to tear the other down.
Clinton has repeatedly criticized Trump for mocking a disabled reporter earlier in the campaign, suggesting that is among the reasons why Trump lacks the temperament to be president.
In other recent addresses, including one in Philadelphia on Monday aimed at millennials, Clinton has also sought to humanize herself, acknowledging that she is not comfortable with all aspects of being a public figure.
During Clinton’s speech on Wednesday, an aide said, she will argue that the one in five Americans with disabilities “are too often overlooked” and recount her work on their behalf, starting with her days as a young lawyer at the Children’s Defense Fund.