House Democrats on Friday delivered a stinging defeat to President Barack Obama’s trade agenda when a vast majority voted to derail legislation designed to help him advance a sweeping deal with Asian nations.

The Washington Post’s David Nakamura and Paul Kane report:

The House voted to sink a measure to grant financial aid to displaced workers, fracturing hopes at the White House that the package would smooth the path for Congress to approve a separate bill to grant Obama fast-track authority to complete an accord with 11 other Pacific Rim nations.

“I will be voting to slow down fast-track,” House Minority Leader Nancy Pelosi (D-Calif.) said on the floor moments before the vote, after keeping her intentions private for months. “Today we have an opportunity to slow down. Whatever the deal is with other countries, we want a better deal for American workers.”

The setback for the president followed months of intense lobbying by the White House.

After attending Thursday’s annual congressional baseball game, Obama made a last-ditch visit to Capitol Hill Friday morning in an attempt to convince Democrats to support the deal.

Opponents of the fast-track bill come from many factions within the House Democratic Caucus, the Post’s Kelsey Snell reports:

This coalition includes avowed liberals like Keith Ellison (D-Minn.), the chairman of the House Progressive Caucus and Danny Davis (D-Ill.), who say they have watched trade deals decimate their local economies and cannot support new agreements, no matter who is in the White House … It also contains members from manufacturing heavy states like Rep. Sandy Levin (D-Mich.), the ranking member of the House Ways and Means Committee.