Reasons for the delay were not clear early Tuesday, but Democratic aides said that pressure by Minority Leader Charles E. Schumer (D-N.Y.) to spread out the hearings appeared to be working.
Republican aides on the committee confirmed that the hearing was postponed until Thursday.
A federal ethics office reviewing the billions of dollars of wealth amassed by DeVos and other Cabinet nominees for President-elect Donald Trump under tight deadlines has put strain on investigators.
Given that pressure, the Senate Committee on Health, Education, Labor and Pensions announced Monday that it has postponed a confirmation hearing for DeVos to serve as education secretary until next Tuesday.
That leaves just three hearings now on Wednesday: for Rex Tillerson to serve as secretary of state, Elaine Chao to serve as transportation secretary and the second day of hearings to consider Sen. Jeff Sessions (R-Ala.) as attorney general.