Rafael Marquez's header off a corner kick in the 89th minute sends U.S. to first home loss in a World Cup qualifier since 2001.
Qualifying for the 2014 World Cup in Brazil concludes this week with eight matches: 4 in Europe, 2 in Africa and 2 intercontinental playoffs.
Where to find several World Cup qualifying playoff matches, including Mexico vs. New Zealand, on TV or online.
In its next-to-last World Cup qualifier, the U.S. national team defeated Jamaica, 2-0, to clinch first place in CONCACAF. Graham Zusi and Jozy Altidore scored late goals.
With six weeks and four matchdays remaining in the World Cup qualifying competition, 22 berths in Brazil next summer remain up for grabs.
The U.S. national soccer team welcomes Mexico to Columbus Crew Stadium for a critical World Cup qualifier.
Getting you ready for tonight's World Cup qualifier between the U.S. national soccer team and Mexico at Columbus Crew Stadium .....
How to watch the United States vs. Mexico match and 28 other World Cup qualifiers, plus a Spain friendly, on another busy day of soccer around the globe on Tuesday.
U.S. national team midfielder Michael Bradley was diagnosed with a Grade 2 ankle sprain and, as previously announced, will not play in Tuesday's World Cup qualifier against Mexico in Columbus.
Michael Bradley (ankle injury) has been ruled out of Tuesday's World Cup qualifier against Mexico. Three others are serving yellow card suspensions. To bolster the roster, Juergen Klinsmann added four players.