He will serve as head of the newly established global affairs office, which includes the public relations and public policy teams, Amazon said. And he will report directly to Amazon chief executive Jeffrey P. Bezos, who also owns The Washington Post.
Since leaving the White House in 2014, Carney has most frequently appeared as a talking head on CNN, where he was a paid political analyst and frequent defender of his former boss, President Obama.
But the position was always believed to be a temporary stopping point for the former Time journalist.
Rumors, which ultimately proved to be unfounded, had swirled that he was being courted by Apple.
The hire makes Carney the latest Obama associate to sign on to a gig in the tech world. Last year, car-for-hire startup Uber recruited former Obama campaign manager David Plouffe to lead the company's strategic efforts.
Carney will start his new job Monday. He will give up his CNN position to "focus full-time on Amazon" and will split time between Amazon's D.C. office and its Seattle headquarters, Politico reported.
[This post has been updated and corrected. Jay Carney's last day at the White House was in 2014, not 2013.]