Scott will become the only African-American in the Senate and the first black Republican senator since the 1970s.
When the South Carolinian leaves the Senate next year, who else in the GOP Conference might fill his shoes as a conservative antagonist? There are some possibilities, but the biggest one might be nobody.
South Carolina Gov. Nikki Haley (R) has narrowed her list of potential Senate appointees down to five -- a list that includes former state first lady Jenny Sanford.
"When I look at the U.S. Senate, I say to myself, 'You know what they could use? Another white guy.'"
Haley's decision is totally be up to her, but many are already expecting her to pick Rep. Tim Scott.
The appointee will serve until 2014, when the state will hold two Senate elections.
A key endorsement for Todd Akin's uphill Senate fight also creates an odd alliance between a staunch earmark opponent and a (very) recent convert.