The $225 million initiative, called Resolve, announced Tuesday in New York, aims to reduce the global burden of heart disease and stroke, the world’s leading causes of death. It also will focus on helping low- and middle-income countries fight infectious disease epidemics by strengthening laboratory networks so emerging threats are identified promptly, and training disease detectives to track and investigate disease outbreaks, including those that circulate in animals and jump to humans.
Resolve will be housed in a New York-based public health nonprofit organization called Vital Strategies, which operates in more than 60 countries.
The initiative’s five-year funding is coming from some of the biggest names in global public health: Bloomberg Philanthropies ($100 million), the Chan Zuckerberg Initiative ($75 million) and the Bill and Melinda Gates Foundation ($50 million).
“I hope five years from now we’ll look back and see this was the inflection point for rapid progress in preventing global cardiovascular disease deaths and improving epidemic preparedness,” Frieden said. “In a few years, we hope that blood pressure control, sodium reduction, elimination of trans fats and strong public health systems will have become the new normal.”
Cardiovascular disease causes about 18 million deaths per year, an estimated 31 percent of all deaths worldwide. In lower-income countries, nearly half of those deaths are in people younger than 70, Frieden said.
Progress has stalled because “there is virtually no money going into this space,” he said. “Globally, very few countries are reducing sodium or trans fat or treating high blood pressure effectively.”
But with proven strategies, the initiative aims to save more than 100 million lives over 30 years, he said.
In the United States, progress has also slowed in preventing stroke deaths, according to a CDC report last week. The report did not identify the reasons for the slowdown, but other studies have pointed to increased numbers of Americans with stroke risk factors such as high blood pressure, obesity and diabetes.
Global health security was a top priority for the Obama administration, which created a partnership in early 2014 to prevent deadly outbreaks from spreading, and sought to help countries bolster their capacity to detect and monitor infectious diseases in the wake of the Ebola epidemic.
Although the collaboration has resulted in more than 50 countries posting public “report cards” about their readiness to battle epidemics, “the fact is, most countries are still not prepared and there is limited progress in closing the gaps that have been identified,” Frieden said. “The world now needs to step up and accelerate these countries to close those gaps.”
Bill Gates, co-chairman of the Bill and Melinda Gates Foundation, said: “While our foundation typically focuses on infectious diseases because they disproportionately affect the world’s poorest, we are increasingly concerned about the growing rate of cardiovascular disease in low- and middle-income countries.”
Resolve will also support and work closely with the World Health Organization, the Bloomberg School of Public Health at the Johns Hopkins University, the CDC, the World Bank and the Campaign for Tobacco-Free Kids.
As CDC director, Frieden was often frustrated by the months-long delays in securing critical funding for pressing public health emergencies, such as Zika.
“One of the things that makes me particularly gratified to have this opportunity is the ability to move quickly” and the freedom to choose where to work and with what organizations, he said.
The initiative will have about 10 to 15 staff members in New York City, but also will be able to draw from Vital Strategies’ staff of 100 people in Manhattan and 300 people globally.
A New York native, Frieden is once again working closely with his old boss, former mayor Michael R. Bloomberg, who supported many of the high-profile public health campaigns Frieden started as head of the city's Department of Health and Mental Hygiene. During Frieden’s tenure, the number of smokers dropped significantly, and New York City became the first place in the United States to eliminate trans fats from restaurants and require certain restaurants to post calorie information.
The design of the Resolve initiative will be similar to the program Bloomberg Philanthropies began a decade ago to reduce tobacco use.