The White House withdrew the nomination of Neera Tanden as director of the Office of Management and Budget on Tuesday evening, the first Cabinet-level defeat for the administration. In a statement, President Biden said Tanden, who faced bipartisan opposition from senators because of past comments she made on Twitter, requested that her name be withdrawn.

Meanwhile, Biden said Tuesday that by the end of May, the United States will have enough coronavirus vaccine doses for “every adult in America” who wants one, a goal that he previously projected would be achieved by July.

Here’s what to know:

  • Biden announced that pharmaceutical giant Merck will help make Johnson & Johnson’s single-shot coronavirus vaccine. The unusual pact between the fierce competitors could sharply boost the supply of the newly authorized vaccine, according to senior administration officials.
  • FBI Director Christopher A. Wray told a Senate panel that his agents are pursuing roughly 2,000 domestic terrorism cases — a huge spike as the bureau tries to show it is taking the threat of such attacks seriously in the wake of January’s pro-Trump riot at the U.S. Capitol.
  • Rhode Island Gov. Gina Raimondo (D) won Senate confirmation as the next commerce secretary, a post that will thrust her into the middle of some of the most contentious economic and security issues confronting the Biden administration.
  • The administration announced it is imposing sanctions on Russia over the poisoning and jailing of opposition leader Alexei Navalny, a fierce critic of Russian President Vladimir Putin.
  • New York Gov. Andrew M. Cuomo (D) is facing growing calls to resign after a third woman accused him of unwanted advances. He has referred allegations of sexual harassment against him to the state’s attorney general.