Another week, another rash of injuries. Pittsburgh Steelers quarterback Ben Roethlisberger suffered a right elbow injury in the first half against the Seattle Seahawks and will miss the remainder of the season. New Orleans Saints quarterback Drew Brees suffered ligament damage to his thumb and is expected to miss six to eight weeks. The New York Jets lost their starting quarterback, Sam Darnold, last week to mononucleosis and then his backup, Trevor Siemian, suffered an ankle injury in Week 2 that will require season-ending surgery. Philadelphia Eagles tight end Dallas Goedert, wide receiver Alshon Jeffery and running back Corey Clement all suffered injuries against the Atlanta Falcons. Dallas Cowboys wide receiver Michael Gallup needs an MRI on his knee and Steelers running back James Conner suffered a knee injury as well, adding two more players to the questionable list for Week 3.

That’s a lot of roster spots to fill. Here’s a road map to help you create a lineup for Week 3.

Start

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Jimmy Garoppolo, QB, San Francisco 49ers

After a shaky preseason, Garoppolo is starting to find his groove. The 27-year-old has completed 35 of 52 passes for 463 yards and four touchdowns, making him the eighth-most valuable passer of 2019, per ESPN’s Total Quarterback Rating.

His opponent this week, the Pittsburgh Steelers, acquired defensive back Minkah Fitzpatrick from the Miami Dolphins to help improve a secondary that ranks 25th, per the game charters at Pro Football Focus, but it is unlikely Fitzpatrick will be able to make an impact in his first week with the team. Instead, look for Garoppolo and the 49ers to find success against a pass defense that is allowing 15 points more per game via the pass after accounting for the down, distance and field position of each throw against. Only the New York Giants and Miami Dolphins have been worse in 2019, per data from TruMedia.

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Case Keenum, QB, Washington Redskins

The Redskins have struggled this season but little of the blame can be laid at the feet of Keenum. He’s completed 56 of 81 passes for 601 yards, five touchdowns and no interceptions, leading to a career-high passer rating of 111.2.

Washington also passes the ball more when they are trailing, which should give Keenum plenty of opportunities to throw the ball on Monday night against the Chicago Bears. The Redskins are passing 95 percent of the time (!) when trailing by 11 or more points. Chicago is a four-point favorite over Washington in Week 3, implying a 66 percent win probability for the Bears and plenty of time for the Redskins to trail in the game.

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Frank Gore, RB, Buffalo Bills

Gore, not rookie Devin Singletary, leads the Bills in rushing attempts (30 to 10) and the 36-year-old figures to get more of the team’s workload if Singletary, who suffered a hamstring injury in Sunday’s win over the New York Giants, doesn’t heal quickly.

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But Gore has shown he is the lead back for this team even with Singletary active. And Sunday’s opponent, the Cincinnati Bengals, allowed 259 rushing yards to the 49ers in Week 2. Plus, Gore is available in 77 percent of fantasy leagues, making him a decent waiver wire pickup for Week 3.

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Aaron Jones, RB, Green Bay Packers

Jones has 36 carries for 155 yards and a touchdown in 2019 but will have trouble finding running room against the Denver Broncos in Week 3. Denver, despite being 0-2, has the sixth-best run defense, per Pro Football Focus, with 11 different players making at least one stop (defined by PFF as an offensive gain on first down that is kept to less than 40 percent of the line to gain, less than 50 percent of the line to gain on second down or any third- or fourth-down play kept without a first down or touchdown).

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Denver linebacker Josey Jewell has a team-high eight stops by himself (sixth most among linebackers this year) and will be a major factor in limiting Jones in the open field.

Andy Dalton, QB, Cincinnati Bengals

Some owners will be scrambling to find an injury replacement at quarterback, but this isn’t the week to start Dalton. He will have to face the second-best pass-rushing unit and eighth-best secondary in the Buffalo Bills, according to Pro Football Focus.

Plus, the Bengals’ offensive line has already yielded 29 pressures (sacks, hits and hurries), the second most this season. Since 2017, Dalton’s passer rating drops from 92.8 in a clean pocket to 78.0 when facing pass pressure.

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Curtis Samuel and D.J. Moore, WR, Carolina Panthers

Quarterback Cam Newton had a dismal game against the Tampa Bay Buccaneers and on Friday was declared out for Sunday’s game against the Arizona Cardinals. That means we should see backup Kyle Allen, an undrafted free agent, under center.

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It certainly makes sense to downgrade Carolina’s top two receivers this week, but they were spotty plays in any case. Newton has completed 24 of 41 passes to the two wideouts this season for 288 yards and no touchdowns. In turn, Samuel and Moore are only producing an average of 3.8 yards after the catch, a huge drop for the duo from its 2018 average of 6.1. Allen completed 3 of 9 passes to Samuel and Moore during the preseason for 24 yards and no touchdowns.

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