Valparaiso clawed back, getting within one point on two occasions but in the last minutethe Panthers made 7 of 8 free throws for their fourth-straight win.
Isaiah Brown had 16 points and six assists for Northern Iowa (15-2, 4-1 Missouri Valley Conference), Trae Berhow added 15 points and Austin Phyfe scored 15 with eight rebounds.
Northern Iowa scored a season-high 52 second-half points.
Javon Freeman-Liberty scored 28 points with eight rebounds for the Crusaders (9-9, 2-3), Ben Krikke added 13 and Mileek McMillan 11.
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