Colts quarterback Peyton Manning is listed as doubtful for Sunday’s opener at Houston, jeopardizing his streak of consecutive games started at 208. Manning had neck surgery in May to have a disk problem repaired. (Darron Cummings/Associated Press)

Quarterback Peyton Manning has been told to temporarily stop practicing and his playing status for the Indianapolis Colts’ opening game of the season Sunday at Houston is expected to be listed as doubtful, the team announced Monday.

It would be the first missed game of Manning’s career as he enters his 14th NFL season. He has started each of his 208 regular season games with the Colts. Counting the postseason, he has made 227 consecutive starts.

Manning, 35, underwent surgery in May to have a disk problem in his neck repaired. Manning said last week that he remained hopeful of playing against the Texans in the opener. But the Colts announced Monday that “the rate of improvement in Peyton’s rehabilitation process slowed” over the past week and he underwent further tests after experiencing soreness in his back over the weekend.

“As a result of the most recent development the doctors have decided that Peyton will not practice,” the team said in a statement. “His participation therefore, in Sunday’s game versus Houston will likely be doubtful. We will update his playing status as required by NFL policy as the week goes on.”

The Colts’ statement said the team’s medical staff is consulting with specialists and Manning won’t participate in practices for now.

“At the conclusion of the diagnostic process, if there are any new developments in the prognosis which we outlined for Peyton at the start of training camp we will report them,” the team’s statement said. “As of now Peyton continues to deal with a complicated neurological recovery, the end date of which is unpredictable.”

The four-time league most valuable player is entering the first season of a new five-year, $90 million contract.

The Colts lured veteran quarterback Kerry Collins out of retirement during the preseason to join Manning’s backup, Curtis Painter, on the roster.