Orioles third baseman Manny Machado injured his knee Aug. 11 and will have season-ending surgery to repair it. (Patrick Semansky/Associated Press)

Nothing went right for the Baltimore Orioles as they opened a series against the Chicago Cubs on Friday.

Not only did the Orioles lose, 4-1, to former Baltimore right-hander Jake Arrieta, but they learned any postseason run this year will be made without third baseman Manny Machado.

Machado, on the disabled list with what the team diagnosed as a right knee sprain, will have season-ending surgery, according to an industry source.

The 22-year-old Machado injured his right knee Aug. 11 when he fell to the ground following through on a swing.

This will be the second consecutive year Machado’s season ends with a knee injury. Last September, he suffered a torn patellofemoral ligament in his left knee that required surgery and caused him to miss the first month of the season.

The Orioles have not made an announcement regarding Machado, but Executive Vice President Dan Duquette will discuss the situation before Saturday’s game.

The club hasn’t revealed much information about Machado’s injury, never announcing the grade of the sprain or the ligament affected.

Yahoo Sports first reported Machado will undergo knee surgery.

Meanwhile, Arrieta said it was different pitching against his old team at Wrigley Field, facing so many familiar faces.

Arrieta was a home-grown Oriole, once a can’t-miss piece of the club’s vaunted “calvary” group of young pitchers. But he struggled to find consistency in an Orioles uniform, leading to a trade that sent him to the Cubs in July 2013.

But Arrieta is flourishing, and he stifled the Orioles’ bats, allowing just one run on four hits over seven innings to snap the Orioles’ four-game winning streak.

“I think he looked more mature,” said Orioles left fielder Nelson Cruz, who didn’t play with Arrieta but faced him when Cruz was with the Rangers. “He was commanding all his pitches, and he didn’t make many mistakes. He’s a great pitcher. We tried to battle and try to get as many runs as we can, but unfortunately it wasn’t our day.”

For a team with little to get excited about this time of year, Arrieta has emerged as the Cubs’ ace, posting 14 quality starts in his last 15 outings. He has allowed two runs or fewer in five of his last six starts.

— Baltimore Sun