Updated at 9:28 a.m.
Officials said the earlier crash on Pennsylvania Avenue in Prince George's County has cleared.
But some delays remain on area roads.
Original post at 7 a.m.
Drivers should expect delays in Upper Marlboro, Md., on Wednesday morning, as part of Pennsylvania Avenue is closed after a crash.
At least one person was injured, but the extent of the person's injuries was not immediately known.
Pennsylvania Avenue's westbound side is closed before Woodyard Road. Traffic is being diverted to MD 301.
Delays are mounting and are at roughly five miles in the early morning.