A Maryland Department of Transportation traffic camera shows Interstate 95 traffic Thursday afternoon near the Howard County and Prince George’s County line.

Southbound Interstate 95 reopened Thursday evening at the Prince George’s County-Howard County line after a police pursuit that ended with a fatal crash, authorities said.

The afternoon wreck initially closed I-95 in both directions. All northbound lanes had reopened by around 6 p.m. The southbound lanes reopened around 8:30 p.m., police in Howard County said.

Howard County police said in a statement that they responded to a report of drug activity in a vehicle in the 9100 block of All Saints Road in Laurel around 2:15 p.m. when the driver fled the scene.

When officers attempted to stop the vehicle, the driver went onto northbound I-95 at Route 216 and, investigators believe, tried to make an illegal U-turn into the southbound lane of the interstate at a high speed, when he lost control and was struck by a tractor-trailer.

The driver of the suspect vehicle died, police said, and a passenger in the vehicle was hospitalized in critical condition.

Police said the driver of the tractor-trailer was hospitalized with minor injuries. Another vehicle was run off the road during the crash, according to police, and the driver of that vehicle was hospitalized with minor injuries.

The name of the driver who died was not immediately available.

The wreck closed I-95 in both directions shortly before 3 p.m., with the southbound lanes remaining blocked into Thursday’s evening rush hour. At times, delays stretched more than seven miles in both directions.

Traffic maps showed a snarl of congestion between Washington and Baltimore around 6 p.m., with I-95 and secondary roads clogged from the northern edge of the Washington Beltway to the southern edge of the Baltimore Beltway.