Jury selection is set to begin Monday in the trial of Dzhokhar Tsarnaev, the man accused of carrying out the 2013 Boston Marathon bombing. (Reuters)

His accusers brandish a confession scribbled inside a boat during an intensive manhunt and a video they say shows him placing a backpack with a bomb a few feet from a little boy who died when it exploded seconds later.

His defenders bank on the story of a difficult childhood in a former Soviet republic and his radicalization at the hands of an influential older brother who could have pressured him into participating in the deadly attack.

Jury selection for the trial of Dzhokhar Tsarnaev, accused in the Boston Marathon bombing, begins Monday. Those chosen from a pool of about 1,200 will decide whether Tsarnaev planned and carried out the twin explosions that killed three people and injured more than 260 near the finish line of the race on April 15, 2013. If they find him guilty, they will decide whether he should be put to death.

It’s perhaps the most closely watched federal death penalty case since Timothy McVeigh was convicted and executed for the 1995 Oklahoma City bombing. Tsarnaev’s attorneys tried in vain for months to get the trial moved, arguing that the Boston jury pool was tainted because of the number of locals with connections to the race, and drawing parallels to the McVeigh case, which was moved to Denver for similar reasons. But U.S. District Judge George A. O’Toole Jr. has been unmoved.

Jury selection alone is expected to take several weeks because of extensive media coverage and the thousands of runners, spectators and others in the area affected by the bombing. The process also could be slowed if potential jurors express objections to the death penalty.

As the trial for Boston Marathon bombing suspect Dzhokhar Tsarnaev is set to start Monday, survivor Heather Abbott says she's determined to face him. (Reuters)

Some legal observers say Tsarnaev’s attorneys — facing powerful evidence against him — will probably focus their energies on the penalty phase, when they could present mitigating evidence to spare his life. He has a strong team behind him. Attorney Judy Clarke has a strong record of persuading juries to rule out the death penalty for her high-profile clients, including Ted Kaczynski, the “Unabomber”; Olympic Park bomber Eric Rudolph; and Jared Loughner, who killed six people and wounded U.S. Rep. Gabrielle Giffords (D-Ariz.).

Tsarnaev’s attorneys likely will narrow in on motive and any pressure exerted on him, said Dan Collins, a former assistant U.S. attorney in Chicago who has investigated U.S. ties to terrorism.

“I think his mitigation will be in part paying close attention to what his explanation is and what circumstances beyond his control . . . caused him to do this,” Collins said.

Prosecutors say Dzhokhar, 21, and his brother, Tamerlan Tsarnaev — ethnic Chechens who had lived in the United States for about a decade — carried out the bombing in retaliation for U.S. actions in Muslim countries. Tamerlan, 26, died after a firefight with police several days after the bombing.

Dzhokhar was captured later that day, wounded and bloodied, hiding inside a boat stored in a suburban Watertown yard. Prosecutors said he described a motive in a note written in the boat: “The U.S. Government is killing our innocent civilians,” and, “We Muslims are one body, you hurt one you hurt us all.”

Tsarnaev’s attorneys might lay the groundwork for an explanation involving mental health, said Christopher Dearborn, a professor at Boston’s Suffolk University Law School. That could include any persecution his family could have suffered as ethnic minorities in Kyrgyzstan, where the brothers spent most of their lives before moving to the United States with their parents and two sisters.

“I think the real value in that may be to start to try to generate even a little bit of empathy around this and humanize the kid a little bit, hopefully enough to save a life,” Dearborn said.

Alice LoCicero, a Cambridge, Mass., psychologist and terrorism expert who wrote the book “Why ‘Good Kids’ Turn Into Deadly Terrorists: Deconstructing the Accused Boston Marathon Bombers and Others Like Them,” said she thinks Dzhokhar Tsarnaev might have been susceptible to the influence of his brother and others in part because he had lost structure in the year before the bombings.

Among those life changes: Dzhokhar had left the family’s Cambridge home to attend the University of Massachusetts at Dartmouth; his parents had moved to the volatile Dagestan region of Russia; and the family was having financial trouble. Authorities think Tamerlan became radicalized in the last few years of his life, including during a six-month trip to Dagestan and Chechnya in 2012.

Prosecutors say, however, that Dzhokhar showed signs before the bombing — even to his closest friends — that he was becoming radicalized.

At least one of three college friends convicted of lying or impeding the investigation is expected to testify against him. An additional friend who pleaded guilty to possessing a gun used to kill a police officer during the manhunt is also expected to testify for the prosecution.

Other prosecution witnesses are expected to include people hurt in the bombing, as well as police officers who helped in the aftermath.

Dzhokhar’s defense team has been pushing to show that he may have been intimidated by his brother. Prosecutors revealed in a court filing that Ibragim Todashev, a friend of Tamerlan’s, said Tamerlan participated in a grisly triple slaying in Waltham, a Boston suburb, in 2011.

The trial, expected to last several months, will undoubtedly draw spectators injured in the bombing, as well as supporters of Tsarnaev who have demonstrated outside the courthouse during pretrial hearings. Tsarnaev’s attorneys have asked that the demonstrators be kept at arm’s length.

Heather Abbott, a Rhode Island woman who lost part of her left leg in the bombing, is one of several victims who plan to attend at least part of the trial. She said she hopes to gain some understanding of the motive.

“I don’t see it as something that will get me past the horror of that day,” she said. “It’s something that I will always live with.”

— Associated Press